Hereditary Disorders Mimicking Progressive Multiple Sclerosis
نویسندگان
چکیده
منابع مشابه
Primary-progressive multiple sclerosis.
About 10-15% of patients with multiple sclerosis (MS) present with gradually increasing neurological disability, a disorder known as primary-progressive multiple sclerosis (PPMS). Compared with relapse-onset multiple sclerosis, people with PPMS are older at onset and a higher proportion are men. Inflammatory white-matter lesions are less evident but diffuse axonal loss and microglial activation...
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A number of studies have been conducted with the onset of secondary progressive multiple sclerosis as an inclusion criterion or an outcome of interest. However, a standardized objective definition of secondary progressive multiple sclerosis has been lacking. The aim of this work was to evaluate the accuracy and feasibility of an objective definition for secondary progressive multiple sclerosis,...
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Multiple sclerosis (MS) is a common inflammatory disease of the nervous system that generally starts in young adulthood and over time frequently leads to progressive functional deficits. A characteristic of this still puzzling disease is that its clinical manifestation changes as it progresses. Although during the early phases of the disorder, most patients mainly experience relapses, on averag...
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The hereditary leukodystrophies represent a group of neurological disorders, in which complete or partial dysmyelination occurs in either the central nervous system (CNS) and/or the peripheral nervous system. Adult-onset autosomal dominant leukodystrophy (ADLD) is a slowly progressive, neurological disorder characterized by symmetrical widespread myelin loss in the CNS, and the phenotype is sim...
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recessive lysosomal storage disease caused by a deficiency of arylsulphatase A (ASA). It is characterized by accumulation of sulphatide in the white matter in the central nervous system and peripheral nerves1. The disease is divided in four subtypes, according to onset, severity and progression of the disease: late infantile (before age 4), early juvenile (age 4 to 6), late juvenile (age 6 to 1...
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ژورنال
عنوان ژورنال: Archives of Neuropsychiatry
سال: 2019
ISSN: 1309-4866
DOI: 10.29399/npa.23622